Its a very long heavy engine. Both the 4R100 and BW 1356 have been swapped into rangers the tranny requires the floor to be messaged and possibly a cut/reweld in places, the transfercase will require a notch in the driverside frame rail. It has been done with no ill-effects.
Width is not an issue since its just as wide as the 5.4/4.6 both of which fit. It is 27 1/8" long and 28 1/2" tall. Measure it out and see if you will clear. It will likely require you to mount the radiator under the trim panel and as close foreward as possible, slimline fans and to still mount the engine a little bit into the dash.
I would love to see it done. I was going to originally just swap a 5.4L 3V in and call it good but if the V10 will fit I'm game for the extra HP/TQ.
Been doing a little research just thought I would update you some.
Motor fits like a glove into the F150 even with the added 4" of motor of the 4.6/5.4L. Downside for the one you pulled is it is a drive by wire motor. You may have to get the PCM/throttle body off of a 97/98 and possibly later model van for it to work without swapping in a drive by wire pedal on your truck.