I ran 4g from battery, right along fenderwell, through firewall (there's plenty of space to get in a drill a nice hole or 2 out), under bottom door moulding, mine comes up really easy, pops out with some force, the 4g can sit under the moulding behind the clips. I took it the whole way to the rear of the ext cab, around the back of my system box and to my amp. It's easier than you'll expect. Actually now, my 4g that i first put in is my ground and I put a 0g in under the cab and drilled a hole for that where one of the jumpseats were.
I've taken my door trim off at least 10 times, it still fits perfectly and never broke a clip or anything.