I ran 4.88s with 33's on my sport trac (4.0L auto) and it was fine. 4.56 would have been more ideal, but they worked well in Oregon where the freeway speed limit was 55-65. It was great around town, awesome off road, and manageable on the highway. But I don't think the 3.0L likes to rev like the 4.0L sohc.
My advice is get them if you plan on 33s (unless you spend a lot of time over 70mph). Definitely get them if you plan on 35s. However, the install is really the expensive part so cheap gears really aren't that big of a factor if you ask me.
Edit: I just noticed that you have a 2wd, I probably wouldn't go with 4.88s unless you are planning on going with 35s.
2006 F150 FX4 Super Crew - Bilstien 5100s leveled 2", 35" KM2s, 4.56 gears, Detroit locker, Eaton E-Locker, Traction Bars, AEM intake, Xcal 2
2010 VW Golf TDI 6MT