I never had hub/bearing issues on the ranger or sport trac, I did have to replace upper and lower balljoints, inner and outer tie-rod ends after some time on the ranger. The 33's went on around 80k miles if I guess, and the balljoints not far behind. Though they held up pretty well until I sold it with 140k miles, probably due to be replaced again at that point.
I wouldn't say anything wore out significantly faster than with 31's. A proper wheel will help things, I always had 15x8's with (I think) 3.75-4" of backspacing. If you use a wide 10" wheel you are putting significantly more stress on the ball joints and hub/bearing assemblies.
2006 F150 FX4 Super Crew - Bilstien 5100s leveled 2", 35" KM2s, 4.56 gears, Detroit locker, Eaton E-Locker, Traction Bars, AEM intake, Xcal 2
2010 VW Golf TDI 6MT