so if i got this right, you wanna take a new front clip (i'm assuming mid to late 90s or newer) and put it on the boxy style of the 90's cab and bed. correct? if so your lines won't line up and it would look like garbage.
if you mean just replacing the fenders with new ones and a new grill, go for it.
as for the chopping of the wheelwells, i'm not getting what you mean. you say you wanna cut the area behind the wheelwell but then you'd have eggshaped wheelwells.