my truck with basically 35's. i have a metric tire size but it equates to a 34.8 or some ****
now everyone's gonna say regear, and i will agree. depending on what motor you have.
mine on 4.10's isnt the worst thing i've driven in the world, keeps speed on the highway just fine. but it could use a little more oomph and i will be regearing to 4.56's eventually. it just isnt a very pressing matter at the moment.
i LOVE having this size tires. and i wouldnt suggest wheeling it. im on 16x8's with almost stock backspacing. maybe a little less.