Actually, the 2.3L turbo guys play with it quite a bit. Because ethanol burns a good bit colder than regular petroleum, it is popular for very high boost applications (usually seen with HX35 or bigger turbos running 30psi+). Although water/meth injection or separate race gas tunes are more popular, guys are pushing 10s on E85 with daily drivers.
Of course, at that point they are all running some sort of tuning program and have their trucks tuned to it. It's mostly seen as an alternative water/meth injection. Me personally, if I ever push over 25psi on an HX35 I'm going with ethanol. All you do is tune for it and fill it up, just have to watch those o-rings and fuel lines.