it depends how it is out of alignment. if the toe (the wheels direction in relation to each other, basically looking down on them they would look like / \ only not as severe LOL) it will cause pulling or some kind of handling issues.
if the camber is off, it should not affect handling. camber is the wheels looking like / \ form the front or back of the truck. you camber will go out of alignment slightly with a T bar crank.
your toe(more important generally) should not be affected.