So uh, I need to replace the lock ***** on my 99' Ranger. Anyone know how to get them off? Do I need to take off the entire door panel? Anyone know? Because they don't just twist off as far as I can tell.

 

These interior lock pulls should be threaded, yours may be just too tight to get off with your fingers just use some pliers on them.

Since you are replacing them just look inside the new pulls and you should see the threads.