I have a cylinder 5 Missfire on my 2010, I've replaced plugs, wires, coils, and listened to the injector and it sounds fine. What should check next? The engine light has gone off on its own once and I've cleared it after each 'fix' but it keeps coming back after a little while. This is the first truck that I've been actively trying to work on myself so any guidance would be appreciated.

 

How many miles on your 2010?
Ground circuit to the #5 injector might be a problem.
Maybe check the engine's computer board for water incursion and corrosion?

 

It's got 146k miles

 

Did you find out what was problem with your misfire?