A little over 20k miles ago I was having these same issues.

CEL indicating that both bank 1 and 2 are lean, misfire in cylinder 1, and misfire detected within first 1000 revs. (P0316)

I changed my coil pack out and it fixed the issue. But now 20k later I'm having the same problem. Could the coil pack of failed that quickly? I replaced it with a BWD pack from pepboys.

I have check for vacuum leaks and everything appears fine. I hacked off some of my tailpipe because I bent it on a trail. Not sure if that means anything. Just did radiator flush and has been maintained pretty well for the most part. Also just changed fuel filter.

I'm at 117k now.

Could the cam syncro failing cause these issues?

**Its a 2004 Ranger Edge 3.0 2wd

 

Still could be a bad coil pak, Bad plug or wire. The coil pack might still be warranty(lifetime) :

 

I will check spark tonight and see what I come up with.