Okay here is the deal. Rebuilt the 3.0 in my 2000 ford ranger. Fired Up had a miss but thought it'll clear up. Engine ran rough then cleared up. Restarted it engine ran good then got rough again and died. It has fuel and spark and tries to start up nothing. Even backfired back thru throttlebody. Anyone have any ideas

 

If you spray some fuel into the intake will it start up and run then die when that fuel is used up?

If so then I would guess fuel pump is not staying on.
When you turn the key on you should hear the fuel pump in the gas tank run for 2 second.
Turn key on and off several times, you aren't hurting anything, and listen.

After repeating the on and off a few times see if engine starts and runs longer.

Also on the front of the engine behind the Crank pulley is the CKP(crank position) sensor, make sure it is bolted tight to engine and that the connector is on tight.


And I have to ask, how long has the gas in the tank been in there?
The gas in the fuel lines would be fine for a while(no oxygen) but the gas in the tank can go bad after a month or two.
All gas has water in it, and water and gas do not mix.
Water is also heavier than gas, so if the gas in the tank sits long enough then all the water will settle to the bottom(when you are driving is sloshes around and stays mixed in with the gas.
So with all the water settled at the bottom of the gas tank, you start the engine, and where does the fuel pump suck the "gas" in the tank from............the bottom.

Rough running and popping is a common sign of "bad gas", bad gas is gas with too much water in it, which can happen at gas stations given the "wrong" conditions.

 

Yea flushed system but will redo it again as things happen I'll also check the sensor to make sure really tight ..as far as spraying starter fluid it seems to make it backfire.. Thx for those tips I will do them to see. I'm too old school but learning.

 

And one more thing, firing order on the coil pack.

3 4
2 6
1 5
front

or
1 5
2 6
3 4
Front

The drivers side often gets mixed up since passenger side is 1 2 3, people think drivers side should be 4 5 6, it isn't
Ford uses Waste Spark system, and only 3 coils for a V6 engine, so 2 spark plugs fire at the same time, they share a coil.
1 and 5 need to fire at the same time
2 and 6 need to fire at the same time
3 and 4 need to fire at the same time

Those are the "matched pairs" of pistons that balance the engine, 1 and 5 are both at top dead center at the same time, as are 2 and 6, and 3 and 4
it can be
5 1
6 2
4 3

As long as 1 and 5 are on the same coil, and 2 and 6, and 3 and 4