I have a2000 ranger 2wd XLT 4.0

I was driving home and realized that my windows and speedometer hand was not working I cut the truck off and back on and nothing changed everything was working that morning my outside cargo light has also stopped I just put a new radio in and I read the owners guide but I don’t see the fuses listed

Welcome to the forum

Check fuse 26, 10amp, in Cab fuse box for power windows, speedo and cargo light

When you installed the new radio, inside the opening on the left side was the GEM Module, it controls ALL the cab electrical systems
So if fuse 26 is OK then you will need to pull out the new radio and make sure GEM connectors are all still tight and no wires were pulled out

I check the fuse and put a new one in and it popped

Then you've got a fault in the circuit. Time to start tracking it down.

Did you cut the radio wire harness to install the new radio? or did you use a wire adaptor kit?

Yes, short somewhere

Fuse 26 has several connections, see diagram
You have power windows so the lower right diagram

You could pull out the Battery Saver Relay, replace the fuse, leave key OFF!!!!!, and see if fuse blows again
If it does then short is in cluster, GEM or PATS(anti-theft)
Since you just put in a new Radio, GEM is a likely place to get a short in a wire

If you already know it only blows with key on then short is Battery Saver relay or one of its devices, which is power window relay, interior light relay, dash light dimmer, or dome cargo lights